Dr.Jharna Mandal

Dr. Jharna
Select List of Former: 
Former Faculty
Medical Registration number: 
08-6436 (MCI, New Delhi)
Academic Qualifications: 

MBBS, MD (Microbiology)

Special Area of Interest: 
Diarrhoeal diseases, Urinary tract infections, antimicrobial resistance, probiotics, gut microbiome
  1. Shruthi Vasanth, Regina Sumitha Mohanraj, Jharna Mandal. In-vitro study of the effect of Centella asiatica on cholera toxin production and the gene expression level of ctxA gene in Vibrio cholerae isolates. J Ethnopharmacol 2021 Feb 14:113930. Epub 2021 Feb 14.
  2. Naresh Jadhav, Jharna Mandal, Smita Kayal, Jogamaya Pattnaik, Ponraj Madasamy ,Jagdeep Singh, Biswajit Dubashi .Surveillance Stool Culture and its Association with Microbiologically Documented Infection During Febrile Neutropenia in Patients with Acute Leukemia (AL) Undergoing Induction Chemotherapy. November 2020Indian Journal of Hematology and Blood Transfusion. DOI: 10.1007/s12288-020-01377-7.
  3. Anitha Gunalan, Sriram Krishnamurthy, Jharna Mandal. Salmonella enterica Serotype Choleraesuis var Decatur Gastroenteritis Complicated Severe Acute Kidney Injury and Neurological Dysfunction. December 2020 Journal of Gastrointestinal Infections 10(1):36-38. DOI: 10.5005/jp-journals-10068-3040. 
  4. Rachana Kannambath, Subhashree Samantaray, Jharna Mandal, Pazhanivel Mohan. Isolation of Plesiomonas shigelloides from a Case of Inflammatory Bowel Disease on Immunosuppressant Therapy. December 2020 Journal of Gastrointestinal Infections. 10(1):29-30. DOI: 10.5005/jp-journals-10068-3035.
  5. Prashant Bafna, Surendran Deepanjali, Jharna Mandal, Nathan Balamurugan, Rathinam P Swaminathan, Tamilarasu Kadhiravan. Reevaluating the true diagnostic accuracy of dipstick tests to diagnose urinary tract infection using Bayesian latent class analysis. PLoS One 2020 31;15(12):e0244870. Epub 2020 Dec 31.
  6. Ramya Raghavan, Shouao Wang, Nandini Dendukuri, Sitanshu S Kar, Subramanian Mahadevan, Barath Jagadisan, Jharna Mandal. Evaluation of LAMP for detection of from stool samples in children. Access Microbiol 2020 14;2(11):acmi000169.
  7. Shiju K S, Gopichand Pallam, Jharna Mandal, Bibekanand Jindal, Kumaravel S. Use of fosfomycin combination therapy to treat multidrug-resistant urinary tract infection among paediatric surgical patients - a tertiary care centre experience. Access Microbiol 2020 3;2(10):acmi000163. Epub 2020 Sep 3.
  8. Ilanthamizhan Jayakumar, Jayanthi Mathaiyan, Jharna Mandal, Surendran Deepanjali, Sreerag K Sreenivasan. Impact of Therapeutic Drug Monitoring on Once-Daily Regimen of Amikacin in Patients With Urinary Tract Infection: A Prospective Observational Study. Ther Drug Monit 2020 Dec;42(6):841-847.
  9. Sekar K, Krishnamurthy S, Mandal J, Rajappa M. Global DNA Methylation in Children with Complicated Urinary Tract Infection. Arch. Intern. Med. 2020; 092-100.
  10. Kannambath R, Gounassegarane D, Mandal J, Parameswaran S. Recurrent Isolation of Streptococcus pyogenes from a Case of Complicated Urinary Tract Infection. Int J Med Rev Case Rep. 2020; 4: 18-20. doi:10.5455/IJMRCR.
  11. Mohanraj RS, Samanta P, Mukhopadhyay AK, Mandal J. Haitian-like genetic traits with creeping MIC of Azithromycin in Vibrio cholerae O1 isolates from Puducherry, India. J Med Microbiol 2020;69: 372–378
  12. Sugathan S, Mandal J. An in vitro experimental study of the effect of fosfomycin in combination with amikacin, ciprofloxacin or meropenem on biofilm formation by multidrug-resistant urinary isolates of Escherichia coli. J of Med Microbiol 2019; 68:1699–1706
  13. Gopichand P, Agarwal G, Natarajan M, Mandal J, Deepanjali S, Parameswaran S et al. In vitro effect of fosfomycin on multi-drug resistant gram-negative bacteria causing urinary tract infections. Infect Drug Resist. 2019:12 2005–2013.
  14. Natarajan M, Mandal J, Biswal N. Molecular characterization and antimicrobial resistance pattern of diffusely adherent Escherichia coli (DAEC) strains isolated from the children and adults with diarrhoeal symptoms - A study from tertiary referral hospital, puducherry, india. Int J Sci Res. 2019; 8 (3): 1-5.
  15. Bhaskar M, Mandal J. How Important are Enterococci in Causing Urinary tract infections- What do we need to know? A Brief review. Int J Sci Res. 2019;8(1): 32-35.
  16. Ramya Raghavan, Jharna Mandal, Chanaveerappa Bammigatti. Escherichia hermannii - An Unusual Pathogen Causing Urinary Tract Infection. January 2019 Journal of Case Reports. DOI: 10.17659/01.2019.0001
  17. Gopichand P, Agarwal G, Natarajan M, Mandal J, Deepanjali S, Parameswaran S et al. “Is Fosfomycin As Effective As Claimed On MDR Gram-Negative Bacteria Causing UTI?” [Response To Letter]. Infect Drug Resist. 2019; 12: 3091–3092.
  18. Mathew, D. Ponnambath, Jharna Mandal, G. Roy. Enteric Pathogen Profile and Knowledge, Attitude and Behavior about Food Hygiene among Food Handlers in a Tertiary Health Care Center. International Journal of Medicine and Public Health 2019;9(3):60-65.
  19. Ramya Raghavan, Jharna Mandal, Sreerag Kodakkattil Sreenivasan. Isolation of Haemophilus influenzae from Urine of an Elderly Male Patient with Carcinoma Bladder-An Under-recognised Pathogen. May 2018Journal of Clinical and Diagnostic Research 12(5):DD01-DD02 Follow journal. DOI: 10.7860/JCDR/2018/33979.11529
  20. Baskar D, Amalnath D, Mandal J, Dhodapkar R, Vanathi K. Antibodies to Zika virus, Campylobacter jejuni and gangliosides in Guillain-Barre syndrome: A prospective single-center study from southern India. Neurol India. 2018 Sep-Oct;66(5):1324-1331. doi: 10.4103/0028
  21. Natarajan M, Kumar D, Mandal J, Biswal N, Stephen S. A study of virulence and antimicrobial resistance pattern in diarrhoeagenic Escherichia coli isolated from diarrhoeal stool specimens from children and adults in a tertiary hospital, Puducherry, India. J Health Popul Nutr. 2018 Jul 13;37(1):17. doi: 10.1186/s41043-018-0147-z.
  22. Padukone S, Mandal J, Rajkumari N, Bhat BV, Swaminathan RP, Parija SC. Detection of Blastocystis in clinical stool specimens using three different methods and morphological examination in Jones' medium. Trop Parasitol. 2018 Jan-Jun;8(1):33-40. doi: 10.4103/tp.TP_4_18. Epub 2018 May 28.
  23. Rudrabhatla P, Deepanjali S, Mandal J, Swaminathan RP, Kadhiravan T. Stopping the effective non-fluoroquinolone antibiotics at day 7 vs continuing until day 14 in adults with acute pyelonephritis requiring hospitalization: A randomized non-inferiority trial. PLoS One. 2018 May 16;13(5):e0197302. doi: 10.1371/journal.pone.0197302. eCollection 2018.
  24. Ramya Raghavan, Jharna Mandal, Chanaveerappa Bammigatti, Gangadhar Rao.Vibrio vulnificus : An Unusual Isolate from a Case of Eosinophilic Enteritis. December 2017JOURNAL OF GASTROINTESTINAL INFECTIONS 7(1):38-40. DOI: 10.5005/jogi-7-1-38
  25. Padukone S, Mandal J, Parija SC. Severe Blastocystis subtype 3 infection in a patient with colorectal cancer. Trop Parasitol. 2017 Jul-Dec;7(2):122-124. doi: 10.4103/tp.TP_87_15.
  26. Chidambaram M, Parija SC, Toi PC, Mandal J, Sankaramoorthy D, George S, Natarajan M, Padukone S. Evaluation of the utility of conventional polymerase chain reaction for detection and species differentiation in human hookworm infections. Trop Parasitol. 2017 Jul-Dec;7(2):111-116. doi: 10.4103/tp.TP_26_17.
  27. Parija SC, Chidambaram M, Mandal J. Epidemiology and clinical features of soil-transmitted helminths. Trop Parasitol. 2017 Jul-Dec;7(2):81-85. doi: 10.4103/tp.TP_27_17.
  28. J Mandal. Significance of asymptomatic bacteriuria. European Medical Journal. 2017; 2(3):71-77.
  29. Ashokkumar S, Agrawal S, Mandal J, Sureshkumar S, Sreenath GS, Kate V. Hybrid Therapy versus Sequential Therapy for Eradication of Helicobacter pylori: A Randomized Controlled Trial. J Pharmacol Pharmacother. 2017 Apr-Jun; 8(2):62-67.
  30. Mailankody S, Dangeti G.V, Soundravally R, Joseph N.M, Mandal J, Dutta T.K, Kadhiravan T. Cerebrospinal fluid matrix metalloproteinase 9 levels, blood-brain barrier permeability, and treatment outcome in tuberculous meningitis. PLoS One. 2017 Jul 12; 12(7):e0181262.
  31. Thamilselvan P, Muthuraman K.R, Thasan S.A, Kasinathan G, Mandal J, Parija S.C. A Stratified Analysis of Clinical Manifestations and Different Diagnostic Methods of Neurocysticercosis-Suspected Tamilian Population Residing in and Around Puducherry. J ClinDiagn Res. 2017 May; 11(5):DC10-DC15.
  32. Vanathy K, Parija SC, Mandal J, Hamide A, Krishnamurthy S. Detection of Cryptosporidium in stool samples of immunocompromised patients. Trop Parasitol. 2017; 7(1):41-46.
  33. Mandal J, Ponnambath DK, Parija SC. Bioethics: A brief review. Trop Parasitol. 2017 Jan-Jun; 7(1):5-7.
  34. Moolchandani K, Sastry AS, Deepashree R, Sistla S, Harish BN, Mandal J. Antimicrobial Resistance Surveillance among Intensive Care Units of a Tertiary Care Hospital in Southern India. J ClinDiagn Res. 2017; 11(2):DC01-DC07.
  35. Parija S, Ramani S, Mandal J, Hamide A, Bhat V. Detection of chloroquine and artemisinin resistance molecular markers in Plasmodium falciparum: A hospital based study. Trop Parasitol. 2016; 6(1):69.
  36. Das A, Natarajan M, Mandal J. The Emergence of Quinolone Resistant Shigella sonnei, Pondicherry, India. PLoS One. 2016; 11(8):e0160290.
  37. Parija S, Thamilselvan P, Muthuraman K, Mandal J. Rising trends of neurocysticercosis: A serological report from tertiary-care hospital in South India. Trop Parasitol. 2016; 6(2):141.
  38. Mandal J, Ponnambath D, Parija S. Ethics of scientific publication. Trop Parasitol. 2016; 6(2):100.
  39. Parija S, Dinoop K, Mandal J, Swaminathan R, Narayanan P. Comparison of nested-multiplex, Taqman& SYBR Green real-time PCR in diagnosis of amoebic liver abscess in a tertiary health care institute in India. Indian J Med Res. 2016;143(1):4
  40. Parija S, Kumar M, Rajkumari N, Mandal J. A case report of an uncommon parasitic infection of human balantidiasis. Trop Parasitol. 2016; 6(1):82.
  41. Mandal J, Ponnambath D, Parija S. Utilitarian and deontological ethics in medicine. Trop Parasitol. 2016; 6 (1):5.
  42. Gupta P, Mandal J, Krishnamurthy S, Barathi D, Pandit N. Profile of urinary tract infections in paediatric patients. Indian J Med Res. 2015 Apr;141(4):473-7.
  43. Nandhini LP, Biswal N, Adhisivam B, Mandal J, Bhat B V, Mathai B. Synbiotics for decreasing incidence of necrotizing enterocolitis among preterm neonates - a randomized controlled trial. J Matern Fetal Neonatal Med. 2015 Mar 10:1-5.
  44. Banupriya B, Biswal N, Srinivasaraghavan R, Narayanan P, Mandal J. Probiotic prophylaxis to prevent ventilator associated pneumonia (VAP) in children on mechanical ventilation: an open-label randomized controlled trial. Intensive Care Med. 2015 Apr;41(4):677-85.
  45. Mandal J, Dinoop K, Parija SC. Ethics of international collaboration. Trop Parasitol. 2015 Jan-Jun; 5(1):6-8.
  46. Mandal J, Haritha S, Lakshminarayanan S, Parija SC. Utility of Urine Dipstick test for the screening of urinary tract infection in Catheterized Women Following Gynecological Surgeries. J Obstet Gynecol India. DOI 10.1007/s13224-014-0637-x. 
  47. Sangeetha AV, Parija SC, Mandal J, Krishnamurthy S. Clinical and Microbiological Profiles of Shigellosis in Children. J Health Popul Nutr 2014 Dec; 32(4):580-586.
  48. Surumy P. Sulaiman, Singh R, Mandal J. Fungal profile of funguria cases at a tertiary care hospital in southern India. Indian J Med Res 140, October 2014, pp 556-559.
  49. Parija SC, Mandal J, Ponnambath DK. Laboratory methods of identification of Entamoeba histolytica and its differentiation from look-alike Entamoeba spp. Trop Parasitol. 2014 Jul; 4(2):90-5.
  50. Mandal J, Parija SC. Informed consent and research Trop Parasitol. 2014 Jul; 4(2):78-9.
  51. Mandal J, Parija SC. Ethics of sponsored research Trop Parasitol. 2014 Jan; 4(1):2-3.
  52. Mandal J, Parija SC. Ethics of authorship in scientific publications. Trop Parasitol. 2013 Jul; 3(2):104-5.
  53. Mandal J, Sangeetha V, Nivedithadivya, Das A, Parija SC.Characterization of extended-spectrum beta-lactamase-producing clinical isolates of Shigella flexneri. J Health PopulNutr. 2013 Sep; 31(3):405-8.
  54. Mandal J, Parija SC. Ethics of involving animals in research. Trop Parasitol. 2013 Jan; 3(1):4-6.
  55. Krishnamurthy S, Mahadevan S, Mandal J, Basu D. Leptospirosis in association with hemophagocytic syndrome: a rare presentation. Indian J Pediatr. 2013; 80:524-5
  56. Narayanan P, Rustagi RS, Sivaprakasam P, Subramanian M, Parameswaran S, Mandal J, Kaplan BS. Haemolytic uraemic syndrome associated with Pseudomonas aeruginosa sepsis. J Med Microbiol. 2013 Nov; 62(Pt 11):1760-2.
  57. Mandal J, Parija M, Parija SC. Ethics of funding of research. Trop Parasitol. 2012; 2:89-90.
  58. Ajayan P, Krishnamurthy S, Biswal N, Mandal J. Clinical Spectrum and Predictive Risk Factors of Major Infections in Hospitalized Children with Nephrotic Syndrome in Southern India. Indian Pediatr. 2013; 50(8):779-81.
  59. Mandal J, Acharya NS, Buddhapriya D, ParijaSC. Antibiotic resistance pattern among common bacterial uropathogens with a special reference to ciprofloxacin resistant Escherichia coli. Indian J Med Res. 2012; 136:8429.
  60. Mandal J, V G, Emelda J, S M, Parija SC. The Recent Trends of Shigellosis: A JIPMER Perspective. J ClinDiagn Res. 2012 ;6:1474-7.
  61. Mandal J, Preethi V, Vasanthraja R, Srinivasan S, ParijaSC. Resistance to ceftriaxone in Vibrio cholerae. Indian J Med Res. 2012 ;136:674-5.
  62. Mandal J, Sangeetha V, Ganesan V, Parveen M, Preethi V, Harish BN, Srinivasan S, Parija SC. Third-generation cephalosporin-resistant Vibrio cholerae, India. Emerg Infect Dis. 2012 ;18:1326-8
  63. Mandal J, Dinoop KP, Parija SC. Increasing antimicrobial resistance of Vibrio cholerae O1 biotype E1 tor strains isolated in a tertiary-care centre in India. J Health PopulNutr. 2012; 30:12-6.
  64. Mandal J, Giri S, Parija SC. Ethics of editorial and peer review. Trop Parasitol. 2012; 2:4-5.
  65. Mandal J, Halder A. Ethics and clinical research. ParijaSC.TropParasitol. 2011;1:54-6.
  66. Preethi V, Mandal J, Halder A, Parija SC. Trichomoniasis: An update. Trop Parasitol. 2011 ;1:73-5.
  67. Mandal J, Acharya S, Parija SC. Ethics in human research. Trop Parasitol. 2011;1:2-3.
  68. Mandal J, Dhodapkar R, Acharya N.S, Sastry A, Parija S.C. Urinary tract infection due to Aeromonas spp., a lesser known causative bacterium. J Infect Dev Ctries. 2010; 28:679-81.
  69. Mandal J, Mondal N, Mahadevan S, Parija SC.Emergence of resistance to third-generation cephalosporin in Shigella--a case report. J Trop Pediatr. 2010;56:278-9.
  70. Mandal J, Kate A, Parija S.C. Microbicidal effects of electrolysed detergent water. J Hosp Infect.2010; 76:94-95.
  71. Mandal J, Khurana S, Dubey ML, Bhatia P, Varma N, Malla N. Evaluation of direct agglutination test, rk39 Test, and ELISA for the diagnosis of visceral leishmaniasis. Am J Trop Med Hyg. 2008; 79:76-8.
  72. Gautam V, Ray P, Das A, Vandamme P, Malhotra P, Varma S, Vijayvergiya R, Mandal J, Garg N. Two cases of Burkholderia cenocepacia in septicemic patients. Jpn J Infect Dis. 2008 ;61:133-4.
  73. Mandal J, Singhi P.D, Khandelwal N, Malla N. Evaluation of lower molecular mass (20-24 kDa) Taeniasoliumcysticercus antigen fraction by ELISA and dot blot for the serodiagnosis of neurocysticercosis in children. Parasitol Res. 2008 ;102:1097-101.
  74. Shivaprakash MR, Rao P, Mandal J, Biswal M, Gupta S, Ray P, Chakrabarti A. Nocardiosis in a tertiary care hospital in North India and review of patients reported from India. Mycopathologia. 2007; 163:267-74.
  75. Sethi S, Mandal J, Kumar P, Kumar S, Meharwal S, Jindal SK, Sharma M. Susceptibility testing of Mycobacterium tuberculosis by broth microdilution method: a rapid alternative method. DiagnMicrobiol Infect Dis. 2007; 57:447-9.
  76. Chakrabarti A, Das A, Mandal J, Shivaprakash MR, George VK, Tarai B, Rao P, Panda N, Verma SC, Sakhuja V. The rising trend of invasive zygomycosis in patients with uncontrolled diabetes mellitus. Med Mycol. 2006;44:335-42.
  77. Mishra B, Malhotra P, Mandal J, Ratho RK, Varma S. Respiratory syncytial virus is not an important community acquired pathogen in adult haematological malignancy patients. Southeast Asian J Trop Med Pub Health.2006;37;1132-33.
  78. Mandal J, Singhi PD, Khandelwal N, Malla N. Evaluation of ELISA and dot blots for the serodiagnosis of neurocysticercosis, in children found to have single or multiple enhancing lesions in computerized tomographic scans of the brain. Annals of Tropical Parasitology 2006; 100: 39-48 
  79. Ray P, Mandal J, Gautam V, Singh K, Gupta D. A case of pulmonary actinomycosis caused by Actinomyces odontolyticus from India. Indian J Med Res. 2005; 122:547-8.

Chapter in a Book

  1. Subhash Chandra Parija, Jharna Mandal, Dinoop Korol Poonambath, Ajay Haldwr. Ethical Dilemmas and Etiquettes of Scientific Publication. Writing and Publishing a Scientific Research Paper. Springer Nature (India) Pvt. Ltd. 2017;pp189-195.
  2. Jharna Mandal, Subhash Chandra Parija, Ajay Haldar. Writing Thesis for Doctor of Philosophy Course. Springer Nature (India) Pvt. Ltd. 2018; pp273-282.
  3. Regina Sumitha Mohanraj, Gopichand Pallam, Jharna Mandal. Understanding the poor response of biofilm bacteria to antibiotics: An effect of multidrug resistance and persister cells. In Emerging concepts in bacterial biofilms: Molecular mechanisms and control strategies. Edited by Sabu Thomas, D. Prabhakaran. Cambridge Scholars Publishing, England, UK, 2020.
  4. Ramya Raghavan, Jharna Mandal. Use of Bacterial cell wall recycle inhibitors to combat antimicrobial resistance in bacteria. In Antimicrobial Resistance: Global Challenges and Future Interventions. Springer Nature (India) Pvt. Ltd. 2020; pp 189-206.

Books written and edited:

  1. Handbook on antibiotics use in JIPMER 2014 (Third Edition)
  2. Handbook on antibiotics use in JIPMER 2013(Second Edition)
  3. Handbook on antibiotics use in JIPMER 2012 (First Edition)
Positions Held: 
  1. Member secretary of the PhD monitoring committee (),
  2. Member of plantation committee
  3. Member of committee for intramural fund release
  4. Member of committee for selection of sanitary items of central stores
  5. Member of the nodal team for establishment of RT-PCR centers for COVID-19 testing in Pondicherry, Tamil Nadu and Andhra Pradesh (2020-21)
  6. Executive member of the Gastrointestinal Infection Society of India
  7. Member of the Editorial board of the Journal of the Gastrointestinal Society of India
  8. Fellow of the International Medical Sciences Academy
  9. External expert for the board of studies for the postgraduate courses in the Central University of Thiruvarur, Tamil Nadu
Special Clinics: 

Urine & Stool